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3:30 p.m.
in Room 307 of the Optical Sciences Meinel Building
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Speaker: |
Peter So
Massachusetts
Institute of Technology |
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Title: |
Multiphoton Imaging and
Microfabrication for Biology and Medicine |
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Host: |
Michael Descour
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Abstract: |
Multiphoton
microscopy and imaging have found a broad range of applications in
biology and medicine. In this presentation, I will focus on three
important new applications areas. First, high throughput tissue
cytometry will be a new tool for understanding tissue pathological
transformation. We will cover studies carcinogenesis, cardiology,
liver fibrosis, and regenerative medicine. Second, two-photon
fluorescence resonance energy transfer allows protein conformations
to be measured with nanometer scale resolution. We will present a
study using this new methodology to monitor intracellular protein
interactions during mechanotransduction process. Finally, while two-
photon 3D fabrication has been developed for almost two decades, its
utility for making prototype devices is well proven but its
potential utility in manufacturing is limited by its low throughput.
We will present a potentially high throughput method based on
temporal focusing with applications in microfluidic, tissue
engineering, and micro-optics structures. |
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