Optical Engineer for Light-Sheet Microscope Development | University of Minnesota Medical School

Date Posted: 
Monday, May 21, 2018
Position Location: 
Minneapolis, MN
Job Description: 
We are seeking a full or part-time, summer intern (3 months) at the undergraduate, graduate or postdoctoral level, to work in the Cochlear Anatomy Laboratory at the University of Minnesota. Salary commensurate with experience. Minneapolis is a beautiful and fun city, especially in the summer. The University of Minnesota is a large campus with a diverse student population, outstanding recreational sports center, and many cultural activities.
The scanning thin-sheet laser imaging microscope (sTSLIM) has been under development since 2009 with the assistance of 8 German engineering students from the Technical University of Ilmenau, who received their M.S. degrees. sTSLIM consists of two lasers, beam expander, scanning galvanometer, optical elements in a tube, specimen chamber, Orca Flash camera, Olympus MacroMVX microscope with 1X and 2X objectives, and XYZ micropositioners. The system is automated by a custom LabView program. It is a macro light-sheet fluorescence microscope (LSFM) vs. those commercial systems that are designed to image only small, transparent specimens. We image large specimens from a whole zebrafish head, to the human temporal bone, including imaging cochlear implants. It produces high resolution, 2D serial images in a Z or radial stack for 3D reconstruction of anatomical structures. The selected candidate will be responsible for calibration and validation of sTSLIM under the direction of Dr. Peter Santi. The candidate will also work with students and technicians in both the Cochlear Anatomy Laboratory and the University Imaging Center.
The core responsibility of this individual is to continue the development of sTSLIM. This individual’s activities include, but not limited to: • Calibrate the optics for optimal performance • acquire and assemble any additional parts that needed for sTSLIM • Understand and be able to modify existing LabView software for operation of the microscope and for imaging.
The individual should embody and demonstrate our core values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following essential tasks: • Understanding of optics. and precision engineering • Experience with several of the following programs: LabView, Zemax , Fiji, Word, Excel, and Matlab• Ability to work effectively within a team • Ability to work independently when required • Ability to think creatively and problem-solve.

Send CV to: Dr. Peter Santi, Ph.D., Professor of Otolaryngology and Neuroscience, psanti@umn.edu, 612-626-9881