Biomedical Spectroscopy and Interferometry Laboratory

    Fluorescence imaging is a powerful and versatile tool in fundamental and applied biology and biomedical research. Leilei Peng’s Biomedical Spectroscopy and Interferometry Laboratory develops innovative optical microscopy methods for quantitative, functional, three-dimensional fluorescence imaging of live cells and animals. Her group has created a scanning laser-sheet microscope system that employs a two-photon Bessel beam to allow fast 3-D imaging of the deep internal organs of live zebra fish embryos with high spatial resolution, as shown in the figure on the right.

    dual color, two-photon image of fish kidney
    Dual-color two-photon image of zebra fish kidney.